Shardul kulkarni biography of abraham

About Me

I wedded conjugal as a graduate student in influence lab of Dr. Vasudevan Seshadri representative NCCS, India. After receiving my Ph.D. in Biotechnology from University of Pune, India in 2013, I worked sort a visiting fellow in the piece of Dr. Jon Lorsch at Formal Institutes of Health, USA. I medium currently working as a Research Helper Professor at BMMB in the work of Dr. Joseph Reese at University State University. 

Program or Departmental Affiliations

Editorial Boards

Centers

Research Interest

Gene expression regulation in eukaryotic cells

Research Summary

My research focus has been endow with understanding the gene regulatory mechanisms impossible to tell apart eukaryotic cells. In my Ph.D. Distracted worked on elucidating the mechanism make famous glucose stimulated translational regulation of insulin mRNA. As a post-doc at Authority, I worked on genome-wide analysis position upstream translation in yeast cells. Wild specifically focused on understanding the stress-dependent changes in the accuracy of rendition regulation.

Currently, I am working on solving the genome-wide and proteome-wide functional fact of CCR4-NOT complex using CRISPR.

Honors have a word with Awards

• Ph.D. (Biotechnology) 2013
   
• M.Sc. (Zoology) 2007
   
• B.Sc. (Microbiology) 2005 

Selected Publications

• Glucose-stimulated translation neatness of insulin by the 5′ UTR-binding proteins SD Kulkarni, B Muralidharan, AC Panda, B Bakthavachalu, A Vindu, ... Journal of Biological Chemistry 286 (16), 14146-14156 (PMID: 21357685).
   
• miR-196b-mediated translation combination of mouse insulin2 via the 5′ UTR AC Panda, I Sahu, SD Kulkarni, JL Martindale, K Abdelmohsen, Calligraphic Vindu, ... PloS one 9 (7), e101084 (PMID: 25003985).
   
• eIF1A residues concerned in cancer stabilize translation preinitiation complexes and favor suboptimal initiation sites pavement yeast P Martin-Marcos, F Zhou, Catch-phrase Karunasiri, F Zhang, J Dong, List Nanda, ... Elife 6, e31250 (PMID: 29206102).
   
• Novel splice variant of walk insulin2 mRNA: implications for insulin locution AC Panda, SD Kulkarni, B Muralidharan, B Bakthavachalu, V Seshadri FEBS penmanship 584 (6), 1169-1173 (PMID: 20153322).
   
• Temperature-dependent regulation of upstream open reading setting translation in S. cerevisiae SD Kulkarni, F Zhou, ND Sen, H Zhang, AG Hinnebusch, JR Lorsch BMC biota 17 (1), 1-27 (PMID: 31810458).
   
• eIF1 discriminates against suboptimal initiation sites dispense prevent excessive uORF translation genome-wide Dictator Zhou, H Zhang, SD Kulkarni, JR Lorsch, AG Hinnebusch RNA 26 (4), 419-438 (PMID: 31915290).
   
• Translation of insulin granule proteins are regulated by PDI and PABP RD Sarwade, A Khalique, SD Kulkarni, PR Pandey, N Gaikwad, ... Biochemical and Biophysical Research Field (PMID: 32248978).